What is Phenylketonuria (PKU)?
Phenylketonuria (PKU) is a rare inherited metabolic disorder. It occurs when the body lacks an enzyme called Phenylalanine hydroxylase, which is required to break down the amino acid Phenylalanine (found in milk and protein foods). When phenylalanine builds up in the blood, it becomes toxic to the brain and nervous system, leading to developmental disabilities, seizures, and growth delays if untreated.
Causes of PKU
Genetic Disorder (Autosomal Recessive) → Both parents carry the defective gene and pass it to the child.
This causes absence or malfunction of Phenylalanine hydroxylase enzyme.
Result: Phenylalanine from protein cannot be converted into Tyrosine → toxic buildup occurs.
Symptoms of PKU (if untreated)
- Persistent vomiting and feeding problems
- Seizures and tremors
- Musty odor in urine or breath
- Skin rashes (eczema-like)
- Irritability, excessive crying
- Poor weight gain and developmental delay
- Long-term: Intellectual disability and brain damage
Prevalence in Pakistan
Worldwide incidence: about 1 in 10,000 to 15,000 births
Pakistan has a higher risk due to consanguineous marriages (cousin marriages)
Local studies estimate: 1 in 6,000–8,000 births may be affected
With ~5.5 million births annually, ~700–900 infants each year in Pakistan could be born with PKU
Biggest challenge: No national newborn screening program → many children diagnosed late when brain damage has already started
Management of PKU
PKU has no permanent cure. Management depends on strict lifelong dietary control.
1. Special Medical Formulas: Phenylalanine-free formulas (like Feelac Premium PKU) are essential for infants from birth. Provide safe amino acids and complete nutrition without toxic buildup.
2. Low Protein Diet: Natural protein foods (milk, meat, eggs, cheese) are avoided. Only fruits, vegetables, and special low-protein foods allowed under dietitian guidance.
3. Regular Monitoring: Frequent blood tests for phenylalanine levels, Growth and developmental assessments
4. Medicines (in some countries): Sapropterin (Kuvan®) and Pegvaliase (Palynziq®) are available internationally for some cases. Not available in Pakistan, so diet + formula remain the only treatment.
The Solution: Feelac Premium PKU (Infant Formula Milk From)
Milk is sourced from Holland & New Zealand cow breeds, raised on natural grass-based feed. Every tin is made with premium French-selected ingredients, Malacian Halal Certified, and compliant with WHO, Codex Alimentarius & ISO 22000 standards.
Key Features
Phenylalanine-Free → Prevents toxic accumulation
Amino Acid-Based Nutrition → Safe protein substitute
DHA & ARA → Brain and vision development
Nucleotides + Micronutrients → Immunity and gut support
Calcium + Vitamin D + Phosphorus → Strong bones & skeletal growth
Halal Certified (JAKIM Malaysia) | 
WHO & ISO Standards
Especially valuable in Pakistan where mother’s milk is not sufficient or available, and cow’s milk protein is unsafe due to PKU.Customer Care & Product Availability
📞 Helpline / WhatsApp: +92 300 9693126 | 0345 4699975
Our team will guide you to the nearest pharmacy or arrange product availability through our distribution network.
Important:
Breast milk is the optimal nourishment for your baby. It contains everything your child requires for healthy growth and development. We recommend breastfeeding for your child . However, if you need to use a bottle, our formula offers an appropriate alternative.